Peng Jiang

Combinatorial Code Analysis for Understanding Biological Regulation Peng Jiang

An important mechanism to achieve regulatory specificity in diverse biological processes is through the combinatorial interplay between different regulators, such as amongst transcription factors during transcriptional regulation or between RNA binding proteins and microRNAs during transcript degradation control. To advance our understanding of combinatorial regulation, this book systematically describes the computational methodology for predicting genome-wide co-binding between biological regulators.